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Participants Adults aged 18 years who were residents in Saudi Arabia and had used nicotine pouches in the past six months were recruited
10.1038/srep43029 Summary Keywords betel quid, Areca catachu , liver fibrosis (LF), metabolic syndrome, hepatotoxicity Citation Chou Y-T, Sun Z-J, Shen W-C, Yang Y-C, Lu F-H, Chang C-J, Li C-Y and Wu J-S (2022) Cumulative Betel Quid Chewing and the Risk of Significant Liver Fibrosis in Subjects With and Without Metabolic Syndrome
The fact that such a large proportion of the sample reported mild to moderate psychological symptoms points to the need for more studies on the safety and long-term effects of nicotine pouch use